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KMID : 0191120220370100050
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Journal of Korean Medical Science
2022 Volume.37 No. 10 p.50 ~ p.50
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Early-Onset Myasthenia Gravis Following COVID-19 Vaccination
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Lee Myung-Ah
Lee Chong-Hwee
Park Jung-Hyun
Lee Jung-Hwan
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Abstract
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As coronavirus disease 2019 (COVID-19) has spread worldwide, the rate of COVID-19 vaccination uptake is encouraging. Neurological complications associated with COVID-19 vaccines such as stroke, Guillain-Barre syndrome, and Bell’s palsy have been reported. Recently, late-onset myasthenia gravis (MG) following COVID-19 vaccination has been reported. To date, however, there has been no evidence of increased risk of early-onset MG following COVID-19. Here, we report a case of a patient with new-onset MG that arose after receiving a COVID-19 vaccine. A 33-year-old woman suddenly experienced generalized weakness and diplopia on the evening she had received the second dose of the Pfizer-BioNTech COVID-19 vaccine. The temporal relationship suggests that this new-onset MG is related to the vaccination. It also implies that COVID-19 vaccination could trigger early-onset MG symptoms in patients at risk of MG.
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KEYWORD
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Myasthenia Gravis, COVID-19 Vaccines, Thymus Hyperplasia
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